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Video or direct laryngoscopy: what the DEVICE trial showed

A trial of 1,417 critically ill adults compared both devices on the first attempt
November 6, 2026 by
Laryngoscope practice on a manikin. Courtesy of PAC.
Laryngoscope practice on a manikin. Courtesy of PAC.

Tracheal intubation of the critically ill happens under pressure: every extra attempt can add hypoxemia and other complications. The DEVICE trial compared video and direct laryngoscopy in real emergency and intensive care practice.

The study

A randomized trial published in the New England Journal of Medicine (Prekker et al., 2023) with 1,417 adults intubated in emergency departments and intensive care units. The primary outcome was successful intubation on the first attempt.

Main results of the DEVICE trial
OutcomeVideo laryngoscopyDirect laryngoscopy
First-attempt success85.1% (600/705)70.8% (504/712)
Absolute difference14.3 percentage points (95% CI 9.9–18.7)—
Severe complications21.4%20.9%

By operator experience

In an exploratory analysis the advantage was larger among less experienced operators:

Exploratory subgroup analysis
Operator's previous intubationsDifference in first-attempt success
Fewer than 2526.1 points (95% CI 15.4–36.8)
25 to 10012.3 points (95% CI 6.8–17.7)

How to read it: first-attempt success is an intermediate outcome, not a direct patient outcome. Commentators point this out as a limitation; the rate of severe complications did not differ between groups.

What it means for training

Our reading: because the benefit appears mostly among operators with less practice, deliberate simulation training with the device is part of procedural safety, not an add-on.

Sources

Image: courtesy of PAC (The Protected Airway Collaborative).

Educational content; it does not replace clinical judgment or your institution's guidelines.

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